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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Mef2d)2Eno
transgene insertion 2, Eric N Olson
MGI:3776912
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Mef2d)2Eno/0 Not Specified MGI:3777091


Genotype
MGI:3777091
tg1
Allelic
Composition		 Tg(Myh6-Mef2d)2Eno/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
liver vascular congestion ( J:130825 )
• liver is severely congested at 8 weeks of age
pulmonary vascular congestion ( J:130825 )
• lungs are severely congested at 8 weeks of age
increased heart atrium size ( J:130825 )
• mice display atrial enlargement at 8 weeks of age
cardiac fibrosis ( J:130825 )
• transgenic animals show extensive fibrosis at 8 weeks of age
cardiomyopathy ( J:130825 )
• hearts display hallmarks of remodeling and cardiomyopathy

muscle
cardiomyopathy ( J:130825 )
• hearts display hallmarks of remodeling and cardiomyopathy

homeostasis/metabolism
abnormal thrombosis ( J:130825 )
• animals show thrombosis at 8 weeks of age

liver/biliary system
liver vascular congestion ( J:130825 )
• liver is severely congested at 8 weeks of age

respiratory system
pulmonary vascular congestion ( J:130825 )
• lungs are severely congested at 8 weeks of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory