cardiovascular system
• liver is severely congested at 8 weeks of age
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• lungs are severely congested at 8 weeks of age
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• mice display atrial enlargement at 8 weeks of age
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• transgenic animals show extensive fibrosis at 8 weeks of age
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• hearts display hallmarks of remodeling and cardiomyopathy
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muscle
• hearts display hallmarks of remodeling and cardiomyopathy
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homeostasis/metabolism
• animals show thrombosis at 8 weeks of age
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liver/biliary system
• liver is severely congested at 8 weeks of age
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respiratory system
• lungs are severely congested at 8 weeks of age
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