Phenotypes associated with this allele

• Allele Symbol: Atcay^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:3776916
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atcay^m1Btlr/Atcay^m1Btlr	C57BL/6J-Atcay^m1Btlr	MGI:3776917

Genotype
MGI:3776917

hm1

• Allelic Composition: Atcay^m1Btlr/Atcay^m1Btlr
• Genetic Background: C57BL/6J-Atcay^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:132743 )

• by 3-4 weeks of age, homozygous mutants frequently fall onto their backs and have difficulty righting themselves

ataxia ( J:132743 )

• although young homozygous mutants are able to move about and to breed, by 8 months of age the ataxia has progressed so the mice no longer can eat

dysmetria ( J:132743 )

• by 3-4 weeks of age, homozygous mutant mice lift their hind legs noticeably higher than do wild-type mice when taking steps

abnormal gait ( J:132743 )

• by 3-4 weeks of age, homozygous mutant mice lift their hind legs noticeably higher than do wild-type mice when taking steps