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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bicc1m1Btlr
mutation 1, Bruce Beutler
MGI:3776918
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bicc1m1Btlr/Bicc1m1Btlr C57BL/6J-Bicc1m1Btlr MGI:3776919


Genotype
MGI:3776919
hm1
Allelic
Composition		 Bicc1m1Btlr/Bicc1m1Btlr
Genetic
Background		 C57BL/6J-Bicc1m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bicc1m1Btlr mutation (1 available); any Bicc1 mutation (65 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:132744 )
• this mutation was discovered in G3 progeny of an ENU-mutagenized male when several mice of a single pedigree died unexpectedly

reproductive system
infertility ( J:132744 )
• mice homozygous for this mutation are viable, but infertile

renal/urinary system
polycystic kidney ( J:132744 )
• by one week of age, kidneys of homozygous mutant mice are enlarged and polycystic

homeostasis/metabolism
increased blood urea nitrogen level ( J:132744 )
• blood urea levels of homozygous mutants are 5-fold normal levels

growth/size/body
polycystic kidney ( J:132744 )
• by one week of age, kidneys of homozygous mutant mice are enlarged and polycystic




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory