All Phenotypes Glra2<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Glra2^tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3777271

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Glra2^tm1Lex/Glra2^tm1Lex	Not Specified	MGI:3810123

Allelic Composition	Glra2^tm1Lex/Glra2^tm1Lex
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glra2^tm1Lex mutation (1 available); any Glra2 mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:132622 )

N	• mice exhibit a normal life span

nervous system

abnormal inhibitory postsynaptic currents ( J:132622 )

• mice exhibit increased decay time of spontaenous glycinergic inhibitory postsynaptic currents (sIPSCs) in narrow field amacrine cells compared to in wild-type mice

• however, the amplitude of glycernergic sIPSCs is normal

reproductive system

reproductive system phenotype ( J:132622 )

N	• mice are fertile

growth/size/body

growth/size/body region phenotype ( J:132622 )

N	• mice exhibit normal weight

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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