Phenotypes associated with this allele

• Allele Symbol: Myo5a^d-Btlr
• Allele Name: dilute Bruce Beutler
• Allele ID: MGI:3777919
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo5a^d-Btlr/Myo5a^d-Btlr	C57BL/6J-Myo5a^d-Btlr	MGI:3777922

Genotype
MGI:3777922

hm1

• Allelic Composition: Myo5a^d-Btlr/Myo5a^d-Btlr
• Genetic Background: C57BL/6J-Myo5a^d-Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

diluted coat color ( J:133117 )

• homozygous new gray mice have gray fur

• mice homozygous for the new gray mutation, unlike homozygotes for other mutations at this locus, have black eyes

immune system

immune system phenotype ( J:133117 )

N • new gray mutant mice exhibit normal resistance to mouse cytomegalovirus (MCMV)

N • homozygous mutant mice exhibit normal resistance to Listeria monocytogenes

N • natural killer (NK) cells from new gray mutants exhibit normal degranulation following antibody stimulation of NKp46 or Ly49H receptors, after exposure to YAC-1 cells, or after PMA/ionomycin stimulation

integument

diluted coat color ( J:133117 )

• homozygous new gray mice have gray fur

• mice homozygous for the new gray mutation, unlike homozygotes for other mutations at this locus, have black eyes