Phenotypes associated with this allele

• Allele Symbol: Myo5a^d-2Btlr
• Allele Name: dilute 2 Bruce Beutler
• Allele ID: MGI:3777923
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo5a^d-2Btlr/Myo5a^d-2Btlr	C57BL/6J-Myo5a^d-2Btlr	MGI:3777924

Genotype
MGI:3777924

hm1

• Allelic Composition: Myo5a^d-2Btlr/Myo5a^d-2Btlr
• Genetic Background: C57BL/6J-Myo5a^d-2Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

diluted coat color ( J:133118 )

• mice homozygous for this mutation have gray fur

• mice homozygous for the nut mutation, unlike homozygotes for most mutations at this locus, have black eyes

behavior/neurological

behavior/neurological phenotype ( J:133118 )

N • no neurological defects are evident in homozygous mutant mice

immune system

immune system phenotype ( J:133118 )

N • natural killer (NK) cells from homozygous nut mice exhibit normal degranulation following antibody stimulation of NKp46 or Ly49H receptors, after exposure to YAC-1 cells, or after PMA/ionomycin stimulation

integument

diluted coat color ( J:133118 )

• mice homozygous for this mutation have gray fur

• mice homozygous for the nut mutation, unlike homozygotes for most mutations at this locus, have black eyes