Phenotypes associated with this allele

• Allele Symbol: Txnip^tm1Road
• Allele Name: targeted mutation 1, Roger Davis
• Allele ID: MGI:3778275
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Txnip^tm1Road/Txnip^tm1Road Speer6-ps1^Tg(Alb-cre)21Mgn/Speer6-ps1^+	involves: C57BL/6 * DBA	MGI:3809845
cn2	Txnip^tm1Road/Txnip^tm1Road Tg(Ckmm-cre)5Khn/0	involves: C57BL/6 * FVB	MGI:3809846

Genotype
MGI:3809845

cn1

• Allelic Composition: Txnip^tm1Road/Txnip^tm1Road; Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
• Genetic Background: involves: C57BL/6 * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:132756 )

N • mice exhibit normal viability

reproductive system

reproductive system phenotype ( J:132756 )

N • mice exhibit normal reproduction

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:132756 )

N • mice exhibit normal serum triglyceride, ketone and glucose levels

growth/size/body

growth/size/body region phenotype ( J:132756 )

N • mice exhibit normal growth

Genotype
MGI:3809846

cn2

• Allelic Composition: Txnip^tm1Road/Txnip^tm1Road; Tg(Ckmm-cre)5Khn/0
• Genetic Background: involves: C57BL/6 * FVB

mortality/aging

mortality/aging ( J:132756 )

N • mice exhibit normal viability

homeostasis/metabolism

hypoglycemia ( J:132756 )

increased circulating ketone body level ( J:132756 )

increased circulating triglyceride level ( J:132756 )

improved glucose tolerance ( J:132756 )

reproductive system

reproductive system phenotype ( J:132756 )

N • mice exhibit normal reproduction

growth/size/body

growth/size/body region phenotype ( J:132756 )

N • mice exhibit normal growth