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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
KitW-Btlr
viable dominant spotting Bruce Beutler
MGI:3778370
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
KitW-Btlr/KitW-Btlr C57BL/6J-KitW-Btlr MGI:3778374
ht2
KitW-Btlr/Kit+ C57BL/6J-KitW-Btlr MGI:3778371


Genotype
MGI:3778374
hm1
Allelic
Composition
KitW-Btlr/KitW-Btlr
Genetic
Background
C57BL/6J-KitW-Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-Btlr mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• despite their lack of skin and hair pigment, homozygous mutant mice have black eyes (the classic black-eyed white Kit mutant phenotype)
• the coats of mice homozygous for this mutation are entirely white
• the skin of homozygous mutants is pink

reproductive system
• mice homozygous for this mutation are sterile

hematopoietic system
• homozygotes have few or no mast cells

immune system
• homozygotes have few or no mast cells

integument
• the coats of mice homozygous for this mutation are entirely white
• the skin of homozygous mutants is pink




Genotype
MGI:3778371
ht2
Allelic
Composition
KitW-Btlr/Kit+
Genetic
Background
C57BL/6J-KitW-Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-Btlr mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice heterozygous for this mutation have white patches on the belly

integument
• mice heterozygous for this mutation have white patches on the belly





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory