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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mstntm2Sjl
targeted mutation 2, Se-Jin Lee
MGI:3778375
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mstntm2Sjl/Mstntm2Sjl B6.129-Mstntm2Sjl MGI:3789910
ht2
 		Mstntm2Sjl/Mstn+ B6.129-Mstntm2Sjl MGI:3789914


Genotype
MGI:3789910
hm1
Allelic
Composition		 Mstntm2Sjl/Mstntm2Sjl
Genetic
Background		 B6.129-Mstntm2Sjl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mstntm2Sjl mutation (0 available); any Mstn mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
increased skeletal muscle fiber diameter ( J:132807 )
• mean fiber diameter is increased in gastrocenmius/plantaris muscles, although slightly less than in homozygous Mstntm1Sjl mice
increased skeletal muscle fiber number ( J:132807 )
• muscle fiber number is increased in gastrocenmius/plantaris muscles, although slightly less than in homozygous Mstntm1Sjl mice
increased skeletal muscle mass ( J:132807 )
• significant increase (60-99%) in skeletal muscle mass




Genotype
MGI:3789914
ht2
Allelic
Composition		 Mstntm2Sjl/Mstn+
Genetic
Background		 B6.129-Mstntm2Sjl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mstntm2Sjl mutation (0 available); any Mstn mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
increased skeletal muscle mass ( J:132807 )
• 14-19% increase in skeletal muscle mass




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory