endocrine/exocrine glands
N |
• no obvious abnormality in pituitary development patterns based on examination of makers expression in E18.5
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Allele Symbol Allele Name Allele ID |
Wnt6tm1Akis targeted mutation 1, Andreas Kispert MGI:3778772 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• no obvious abnormality in pituitary development patterns based on examination of makers expression in E18.5
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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• during decidualization, uterine stromal cell proliferation is impaired with prolonged cell cycle length compared with wild-type cells
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• defective decidualization with decreased weight and size of implantation sites
• however, stromal-decidual transformation and polyploidization is normal
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• decreased weight and size of implantation sites
• however, initiation of implantation is normal
|
|
• during decidualization, uterine stromal cell proliferation is impaired with prolonged cell cycle length compared with wild-type cells
|
|
• defective decidualization with decreased weight and size of implantation sites
• however, stromal-decidual transformation and polyploidization is normal
|
|
• during decidualization, uterine stromal cell proliferation is impaired with prolonged cell cycle length compared with wild-type cells
|
|
• during decidualization, uterine stromal cell proliferation is impaired with prolonged cell cycle length compared with wild-type cells
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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