About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stim1tm1.1Rao
targeted mutation 1.1, Anjana Rao
MGI:3778912
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Stim1tm1.1Rao/Stim1tm1.1Rao involves: BALB/cJ * C57BL/6 * ICR * SJL MGI:3783456
hm2
Stim1tm1.1Rao/Stim1tm1.1Rao involves: BALB/cJ * C57BL/6 * SJL MGI:3783454
cx3
Stim1tm1.1Rao/Stim1tm1.1Rao
Stim2tm1.1Rao/Stim2tm1.1Rao
involves: C57BL/6 MGI:5285572


Genotype
MGI:3783456
hm1
Allelic
Composition
Stim1tm1.1Rao/Stim1tm1.1Rao
Genetic
Background
involves: BALB/cJ * C57BL/6 * ICR * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation (0 available); any Stim1 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 50% of mice that are born alive die by 2 days after birth but die within 2 weeks
• Background Sensitivity: while Mendelian ratios of embryos are present at E18.5, 38% of mice are born dead on a background with ICR compared to 75% without ICR

growth/size/body




Genotype
MGI:3783454
hm2
Allelic
Composition
Stim1tm1.1Rao/Stim1tm1.1Rao
Genetic
Background
involves: BALB/cJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation (0 available); any Stim1 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all mice that are born alive die by 2 days after birth
• Background Sensitivity: while Mendelian ratios of embryos are present at E18.5, 75% of mice are born dead compared to 38% on a background involving ICR

cellular
• mouse embryonic fibroblasts treated with thapsigargin fail to exhibit a calcium influx unlike in wild-type cells




Genotype
MGI:5285572
cx3
Allelic
Composition
Stim1tm1.1Rao/Stim1tm1.1Rao
Stim2tm1.1Rao/Stim2tm1.1Rao
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stim1tm1.1Rao mutation (0 available); any Stim1 mutation (47 available)
Stim2tm1.1Rao mutation (0 available); any Stim2 mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• in mouse embryonic fibroblasts





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory