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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
KitW-2Btlr
viable dominant spotting 2 Bruce Beutler
MGI:3779022
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
KitW-2Btlr/KitW-2Btlr C57BL/6J-KitW-2Btlr MGI:3779024
ht2
KitW-2Btlr/Kit+ C57BL/6J-KitW-2Btlr MGI:3779023
ht3
KitW-2Btlr/Kit+ involves: C3H/HeN * C57BL/6 MGI:3779025


Genotype
MGI:3779024
hm1
Allelic
Composition
KitW-2Btlr/KitW-2Btlr
Genetic
Background
C57BL/6J-KitW-2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-2Btlr mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• despite their lack of skin and hair pigment, homozygous mutant mice have black eyes (the classic black-eyed white Kit mutant phenotype)
• the coats of mice homozygous for this mutation are entirely white

integument
• the coats of mice homozygous for this mutation are entirely white




Genotype
MGI:3779023
ht2
Allelic
Composition
KitW-2Btlr/Kit+
Genetic
Background
C57BL/6J-KitW-2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-2Btlr mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice heterozygous for this mutation have light ears
• heterozygous mutants have a white belly spot
• some heterozygotes have white dorsal spots
• heterozygous mutant mice have light colored tails

craniofacial
• mice heterozygous for this mutation have light ears

hearing/vestibular/ear
• mice heterozygous for this mutation have light ears

limbs/digits/tail
• heterozygous mutant mice have light colored tails

integument
• mice heterozygous for this mutation have light ears
• heterozygous mutants have a white belly spot
• some heterozygotes have white dorsal spots
• heterozygous mutant mice have light colored tails

growth/size/body
• mice heterozygous for this mutation have light ears




Genotype
MGI:3779025
ht3
Allelic
Composition
KitW-2Btlr/Kit+
Genetic
Background
involves: C3H/HeN * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-2Btlr mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot
• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot

integument
• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot
• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory