All Phenotypes Kit<W-2Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kit^W-2Btlr
viable dominant spotting 2 Bruce Beutler
MGI:3779022

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kit^W-2Btlr/Kit^W-2Btlr	C57BL/6J-Kit^W-2Btlr	MGI:3779024
ht2	Kit^W-2Btlr/Kit⁺	C57BL/6J-Kit^W-2Btlr	MGI:3779023
ht3	Kit^W-2Btlr/Kit⁺	involves: C3H/HeN * C57BL/6	MGI:3779025

Allelic Composition	Kit^W-2Btlr/Kit^W-2Btlr
Genetic Background	C57BL/6J-Kit^W-2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-2Btlr mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

pigmentation phenotype ( J:133613 )

N	• despite their lack of skin and hair pigment, homozygous mutant mice have black eyes (the classic black-eyed white Kit mutant phenotype)

absent coat pigmentation ( J:133613 )

• the coats of mice homozygous for this mutation are entirely white

integument

absent coat pigmentation ( J:133613 )

• the coats of mice homozygous for this mutation are entirely white

Allelic Composition	Kit^W-2Btlr/Kit⁺
Genetic Background	C57BL/6J-Kit^W-2Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-2Btlr mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

decreased ear pigmentation ( J:133613 )

• mice heterozygous for this mutation have light ears

diluted coat color ( J:133613 )

belly spot ( J:133613 )

• heterozygous mutants have a white belly spot

variable body spotting ( J:133613 )

• some heterozygotes have white dorsal spots

decreased tail pigmentation ( J:133613 )

• heterozygous mutant mice have light colored tails

craniofacial

decreased ear pigmentation ( J:133613 )

• mice heterozygous for this mutation have light ears

hearing/vestibular/ear

decreased ear pigmentation ( J:133613 )

• mice heterozygous for this mutation have light ears

limbs/digits/tail

decreased tail pigmentation ( J:133613 )

• heterozygous mutant mice have light colored tails

integument

decreased ear pigmentation ( J:133613 )

• mice heterozygous for this mutation have light ears

diluted coat color ( J:133613 )

belly spot ( J:133613 )

• heterozygous mutants have a white belly spot

variable body spotting ( J:133613 )

• some heterozygotes have white dorsal spots

decreased tail pigmentation ( J:133613 )

• heterozygous mutant mice have light colored tails

growth/size/body

decreased ear pigmentation ( J:133613 )

• mice heterozygous for this mutation have light ears

Allelic Composition	Kit^W-2Btlr/Kit⁺
Genetic Background	involves: C3H/HeN * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-2Btlr mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

head blaze ( J:133613 )

• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot

white spotting ( J:133613 )

• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot

integument

head blaze ( J:133613 )

• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot

white spotting ( J:133613 )

• Background Sensitivity: on this mixed genetic background, heterozygous mutants often present with a white belly and a white spindle-shaped forehead spot

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