Phenotypes associated with this allele

• Allele Symbol: Tg(Amelx-Ambn)1Mlp
• Allele Name: transgene insertion 1, Michael L Paine
• Allele ID: MGI:3783594
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Amelx-Ambn)1Mlp/Tg(Amelx-Ambn)1Mlp	Not Specified	MGI:5140073

Genotype
MGI:5140073

tg1

• Allelic Composition: Tg(Amelx-Ambn)1Mlp/Tg(Amelx-Ambn)1Mlp
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal enamel morphology ( J:83576 )

• enamel appears to be more porous

abnormal enamel rod pattern ( J:83576 )

• incisors contain significant areas of enamel with no rod architecture, but with interrod enamel

• enamel of incisor teeth lacks an aprismatic surface layer

• some enamel crystallites exhibit a diameter twice as large as normal crystallites and an axis of 1 um rather than a continuous structure

skeleton

abnormal enamel morphology ( J:83576 )

• enamel appears to be more porous

abnormal enamel rod pattern ( J:83576 )

• incisors contain significant areas of enamel with no rod architecture, but with interrod enamel

• enamel of incisor teeth lacks an aprismatic surface layer

• some enamel crystallites exhibit a diameter twice as large as normal crystallites and an axis of 1 um rather than a continuous structure

growth/size/body

abnormal enamel morphology ( J:83576 )

• enamel appears to be more porous

abnormal enamel rod pattern ( J:83576 )

• incisors contain significant areas of enamel with no rod architecture, but with interrod enamel

• enamel of incisor teeth lacks an aprismatic surface layer

• some enamel crystallites exhibit a diameter twice as large as normal crystallites and an axis of 1 um rather than a continuous structure

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
amelogenesis imperfecta		DOID:2187	OMIM:PS104500	J:83576