All Phenotypes hlb454 MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

hlb454
heart, lung and blood, 454
MGI:3784207

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	hlb454/hlb454	C57BL/6J-hlb454/J	MGI:3784208

Allelic Composition	hlb454/hlb454
Genetic Background	C57BL/6J-hlb454/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb454 mutation (1 available); any hlb454 mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

respiratory system

increased airway responsiveness ( J:82961 )

• mice homozygous for this mutation exhibit airway hyperresponsiveness to methacholine (MCH) challenge as measured by whole body plethysmography; this phenotype has been verified by an invasive resistance evaluation using a flexivent protocol

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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