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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		hlb454
heart, lung and blood, 454
MGI:3784207
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		hlb454/hlb454 C57BL/6J-hlb454/J MGI:3784208


Genotype
MGI:3784208
hm1
Allelic
Composition		 hlb454/hlb454
Genetic
Background		 C57BL/6J-hlb454/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb454 mutation (1 available); any hlb454 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
increased airway responsiveness ( J:82961 )
• mice homozygous for this mutation exhibit airway hyperresponsiveness to methacholine (MCH) challenge as measured by whole body plethysmography; this phenotype has been verified by an invasive resistance evaluation using a flexivent protocol




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory