Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(Dmp1-cre)1Jqfe transgene insertion 1, Jian Q Feng MGI:3784520 |
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| Summary |
5 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal tooth eruption
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• at 12 weeks of age
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• filling the bone marrow cavity at 12 weeks of age
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• with age beginning postnatally
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• severe postnatally
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• mice exhibit cartilage remnants unlike control mice
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• bone formation is decreased compared to in control mice
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| N |
• mice exhibit normal growth
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal tooth eruption and growth plates
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• mice suspended by their tails for 3 weeks are protected from loss of bone and changes in cancellous architecture compared with similarly treated wild-type mice
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• mice suspended by their tails for 3 weeks do not exhibit an increase in osteoclast number compared with similarly treated wild-type mice
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• BMD increases progressively in the spine
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• BMD increases progressively in the femur
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• at 6 months of age in the femur and spine
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• in mice suspended by their tails for 3 weeks
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• mice suspended by their tails for 3 weeks exhibit increased trabecular spacing compared with similarly treated wild-type mice
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• mice suspended by their tails for 3 weeks do not exhibit an increase in osteoclast number compared with similarly treated wild-type mice
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• mice suspended by their tails for 3 weeks do not exhibit an increase in osteoclast number compared with similarly treated wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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