Analysis Tools
mortality/aging
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• all embryos die prior to E10.5
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• most embryos do not survive past E6.5
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Allele Symbol Allele Name Allele ID |
Wdr1Gt(XN462)Byg gene trap XN462, BayGenomics MGI:3784953 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• all embryos die prior to E10.5
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• most embryos do not survive past E6.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die between 3 and 6 weeks of age
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• mice exhibit runting by 3 weeks of age compared to wild-type littermates
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• spontaneous inflammatory lesions occur on the outside portions of the ear by 3-6 weeks of age
• inflammatory lesions are more severe than in Wdr1rede homozygotes
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• mice have severe inflammation characterized by pustular lesions on the lower ventum
• inflammatory lesions are more severe than in Wdr1rede homozygotes
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• spontaneous inflammatory lesions occur on the outside portions of the ear by 3-6 weeks of age
• inflammatory lesions are more severe than in Wdr1rede homozygotes
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• three week old mice have 6-fold less platelets per liter of blood compared to wild-type littermates
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• mice have severe inflammation characterized by pustular lesions on the lower ventum
• inflammatory lesions are more severe than in Wdr1rede homozygotes
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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