Analysis Tools
growth/size/body
|
• mice weight less than age- and sex-matched controls at 2, 10, and 15 months of age
• the difference in weight gets larger as mice age with 15 month old mice weighing 30% to 40% less than controls
|
adipose tissue
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• fat content of 10-month old mice is about half that of sex-matched wild-type mice
|
cardiovascular system
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• the mean inner and outer circumferences of the aorta are significantly larger than in littermate controls in the ascending, midthoracic, and descending regions
|
hypotension
(
J:133897
)
|
• mice have lower blood pressure than littermate controls with females having lower blood pressure than the males
• blood pressure of male mice is 116 mm Hg compared to 145 mm Hg for controls
• blood pressure of female mice is 84 mm Hg compared to 144 mm Hg for controls
|
hematopoietic system
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• lymphocyte numbers in the blood are about half that of littermate controls
|
immune system
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• lymphocyte numbers in the blood are about half that of littermate controls
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