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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata6tm1Kgac
targeted mutation 1, Kate G Ackerman
MGI:3785386
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gata6tm1Kgac/Gata6tm1Kgac involves: 129S1/Sv MGI:3789026
cx2
 		Gata4tm1Sho/Gata4tm1Sho
Gata6tm1Kgac/Gata6tm1Kgac 		involves: 129S1/Sv * 129S6/SvEvTac MGI:3789027


Genotype
MGI:3789026
hm1
Allelic
Composition		 Gata6tm1Kgac/Gata6tm1Kgac
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata6tm1Kgac mutation (0 available); any Gata6 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:134027 )
N
• despite expression during lung development, pulmonary lobar structure is normal and no signs of hypoplasia of the accessory lob are detected




Genotype
MGI:3789027
cx2
Allelic
Composition		 Gata4tm1Sho/Gata4tm1Sho
Gata6tm1Kgac/Gata6tm1Kgac
Genetic
Background		 involves: 129S1/Sv * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata4tm1Sho mutation (0 available); any Gata4 mutation (36 available)
Gata6tm1Kgac mutation (0 available); any Gata6 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
abnormal lung development ( J:134027 )
• lungs cultured from E11.5 embryos lack accessory lobe and accessory bud development and show a mild growth delay
• the phenotype of double mutants is not more severe than that of Gata4 single homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory