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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Ins2-E3*734)4Dvs
transgene insertion 4, David V Serreze
MGI:3785757
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Ins2-E3*734)4Dvs/? NOD/ShiLtDvs-Tg(Ins2-E3*734)4Dvs/DvsJ MGI:3785758


Genotype
MGI:3785758
tg1
Allelic
Composition		 Tg(Ins2-E3*734)4Dvs/?
Genetic
Background		 NOD/ShiLtDvs-Tg(Ins2-E3*734)4Dvs/DvsJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-E3*734)4Dvs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to autoimmune diabetes ( J:106340 )
• female carriers of this transgene have slower kinetics and rates of development of diabetes through 30 weeks of age relative to NOD controls and these transgene carriers do not display a significantly different diabetes rate than unmutated adenovirus E3 carriers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory