Phenotypes associated with this allele

• Allele Symbol: Tg(Ins2-E3*734)4Dvs
• Allele Name: transgene insertion 4, David V Serreze
• Allele ID: MGI:3785757
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Ins2-E3*734)4Dvs/?	NOD/ShiLtDvs-Tg(Ins2-E3*734)4Dvs/DvsJ	MGI:3785758

Genotype
MGI:3785758

tg1

• Allelic Composition: Tg(Ins2-E3*734)4Dvs/?
• Genetic Background: NOD/ShiLtDvs-Tg(Ins2-E3*734)4Dvs/DvsJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased susceptibility to autoimmune diabetes ( J:106340 )

• female carriers of this transgene have slower kinetics and rates of development of diabetes through 30 weeks of age relative to NOD controls and these transgene carriers do not display a significantly different diabetes rate than unmutated adenovirus E3 carriers