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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		En2tm5.1Alj
targeted mutation 5.1, Alexandra L Joyner
MGI:3789089
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		En2tm5.1Alj/En2tm5.1Alj involves: 129S6/SvEvTac * Black Swiss * Swiss Webster MGI:3789340
hm2
 		En2tm5.1Alj/En2tm5.1Alj involves: 129S6/SvEvTac * Swiss Webster MGI:4421420
cn3
 		En2tm5.1Alj/En2tm5.1Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ 		involves: 129S2/SvPas * Swiss Webster MGI:4421418


Genotype
MGI:3789340
hm1
Allelic
Composition		 En2tm5.1Alj/En2tm5.1Alj
Genetic
Background		 involves: 129S6/SvEvTac * Black Swiss * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En2tm5.1Alj mutation (1 available); any En2 mutation (104 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reduced fertility ( J:134516 )
• mice are viable but only semi-fertile




Genotype
MGI:4421420
hm2
Allelic
Composition		 En2tm5.1Alj/En2tm5.1Alj
Genetic
Background		 involves: 129S6/SvEvTac * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En2tm5.1Alj mutation (1 available); any En2 mutation (104 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system




Genotype
MGI:4421418
cn3
Allelic
Composition		 En2tm5.1Alj/En2tm5.1Alj
Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S2/SvPas * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En2tm5.1Alj mutation (1 available); any En2 mutation (104 available)
Gt(ROSA)26Sortm1(cre/ERT2)Alj mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:156169 )
N
• following tamoxifen administration at E9.5 - E12.5, foliation pattern is rescued




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory