mortality/aging
• early death found in Lama2 homozygotes is prevented by this transgenic restricted expression of human BCL2 in skeletal muscle, survival exceeds 90 days in all of 6 mice and half lived longer than 120 days
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growth/size/body
• transgenic expression of BCL2 results in increased weight gain and growth rate relative to non-transgenic Lama2 mutants, but does not entirely rescue Lama2 mutants from diminished weight gain and growth
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