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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		In(2)5Rk
inversion, Chr 2, Roderick 5
MGI:3789487
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		In(2)5Rk/In(2)5Rk involves: C57BL/6J * DBA/2J MGI:3789488
ht2
 		In(2)5Rk/+ involves: C57BL/6J * DBA/2J MGI:3789490


Genotype
MGI:3789488
hm1
Allelic
Composition		 In(2)5Rk/In(2)5Rk
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
In(2)5Rk mutation (1 available); any In(2)5Rk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3789490
ht2
Allelic
Composition		 In(2)5Rk/+
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
In(2)5Rk mutation (1 available); any In(2)5Rk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:109968 )
• male heterozygotes have an anaphase bridge frequency of approximately 34% and these are consistently lumpy
female infertility ( J:43743 )
• female fertility is significantly reduced, but male fertility is not

cellular
abnormal male meiosis ( J:109968 )
• male heterozygotes have an anaphase bridge frequency of approximately 34% and these are consistently lumpy




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory