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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		In(12)25Rk
inversion, Chr 12, Roderick 25
MGI:3790093
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		In(12)25Rk/In(12)25Rk involves: C57BL/6J * DBA/2J MGI:3790446
ht2
 		In(12)25Rk/+ involves: C57BL/6J * DBA/2J MGI:3790095


Genotype
MGI:3790446
hm1
Allelic
Composition		 In(12)25Rk/In(12)25Rk
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
In(12)25Rk mutation (1 available); any In(12)25Rk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:23389 )
• homozygous lethal between embryonic day 7 and 10




Genotype
MGI:3790095
ht2
Allelic
Composition		 In(12)25Rk/+
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
In(12)25Rk mutation (1 available); any In(12)25Rk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:23389 )
• male heterozygotes have an anaphase bridge frequency of approximately 73%

cellular
abnormal male meiosis ( J:23389 )
• male heterozygotes have an anaphase bridge frequency of approximately 73%




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory