Analysis Tools
mortality/aging
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• all die within several hours of birth
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cardiovascular system
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• dilation of capillaries beneath areas of the skin where the upper epidermis is detached
• proliferation and dilation of capillaries in skin grafted onto nude mice
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• dilation of capillaries beneath areas of the skin where the upper epidermis is detached
• proliferation and dilation of capillaries in skin grafted onto nude mice
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integument
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• when skin is grafted onto nude mice, hair grows initially but then stops and is lost
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• when skin is grafted onto nude mice, individual hairs are thin and slightly curly
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• when skin is grafted onto nude mice, hair follicles develop abnormal cystic dilations
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• severe infiltration of inflammatory cells in skin grafted onto nude mice
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• the upper epidermis is lost due to detachment of the stratum corneum from the underlying granular layer
• in skin grafted onto nude mice, the infundibular epithelium is thickened
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• extremely low corneodesmosome electron density at E18.5
• desmosomal structures are reduced in number and confined to the lower stratum corneum
• in the stratum corneum of skin grafted onto nude mice, lipid droplets and remnants of nuclei and organelles are seen, fewer keratohyalin granules are present, the electron density of corneodesmosomes is reduced and formation of cornified envelopes is defective
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• in skin grafted onto nude mice
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• in skin grafted onto nude mice
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• loss of the granular layer in skin grafted onto nude mice
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acanthosis
(
J:134613
)
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• in skin grafted onto nude mice
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