About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nat1Rgsc1523
RIKEN Genomic Sciences Center (GSC), 1523
MGI:3793317
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nat1Rgsc1523/Nat1Rgsc1523 involves: C57BL/6 * DBA/2 MGI:3807280
ht2
 		Nat1Rgsc1523/Nat1+ involves: C57BL/6 * DBA/2 MGI:3807281


Genotype
MGI:3807280
hm1
Allelic
Composition		 Nat1Rgsc1523/Nat1Rgsc1523
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nat1Rgsc1523 mutation (0 available); any Nat1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:134504 )
• hepatic N-acteyltransferase 1 activity is reduced by 90% compared to wild-type

reproductive system
reduced fertility ( J:134504 )
• homozygous matings produced only 1 litter each for 2 breeding pairs




Genotype
MGI:3807281
ht2
Allelic
Composition		 Nat1Rgsc1523/Nat1+
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nat1Rgsc1523 mutation (0 available); any Nat1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:134504 )
• hepatic N-acteyltransferase 1 activity is reduced by >50% compared to wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory