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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Csnk1etm1Asil
targeted mutation 1, Andrew S I Loudon
MGI:3793318
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Csnk1etm1Asil/Csnk1etm1Asil involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3804020
ht2
 		Csnk1etm1Asil/Csnk1e+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3804017
ht3
 		Csnk1etm1Asil/Csnk1etm1.1Asil involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3804021


Genotype
MGI:3804020
hm1
Allelic
Composition		 Csnk1etm1Asil/Csnk1etm1Asil
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1etm1Asil mutation (1 available); any Csnk1e mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:135186 )
• significant shortening of circadian period of behavior in vivo in a gene dose-dependent manner
• homozygous mice have 3.6 hr shorter circadian period than wild-type
• mutant mice are viable and fertile with no overt deleterious phenotype

nervous system
abnormal neuron physiology ( J:135186 )
• significant shortening of circadian period of suprachiasmatic nucleus firing rates in vitro in a gene dose-dependent manner




Genotype
MGI:3804017
ht2
Allelic
Composition		 Csnk1etm1Asil/Csnk1e+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1etm1Asil mutation (1 available); any Csnk1e mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:135186 )
• significant shortening of circadian period of behavior in vivo in a gene dose-dependent manner
• heterozygous mice have 1.8 hr shorter circadian period than wild-type
• mutant mice are viable and fertile with no overt deleterious phenotype

nervous system
abnormal neuron physiology ( J:135186 )
• significant shortening of circadian period of suprachiasmatic nucleus firing rates in vitro in a gene dose-dependent manner




Genotype
MGI:3804021
ht3
Allelic
Composition		 Csnk1etm1Asil/Csnk1etm1.1Asil
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csnk1etm1.1Asil mutation (1 available); any Csnk1e mutation (31 available)
Csnk1etm1Asil mutation (1 available); any Csnk1e mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:135186 )
• significant shortening of circadian period identical to heterozygous Csnk1etm1Asil/Csnk1e+ mice
• 1.8 hr shorter circadian period than wild-type
• mutant mice are viable and fertile with no overt deleterious phenotype




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory