Phenotypes associated with this allele

• Allele Symbol: Plxna2^nmf454
• Allele Name: neuroscience mutagenesis facility 454
• Allele ID: MGI:3793765
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plxna2^nmf454/Plxna2^nmf454	involves: C57BL/6J	MGI:3795754

Genotype
MGI:3795754

hm1

• Allelic Composition: Plxna2^nmf454/Plxna2^nmf454
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased neuronal migration ( J:135408 )

• in migrating granule cells the average distance between the centrosome and nucleus is decreased

ectopic cerebellar granule cells ( J:135408 )

• many granule cells are present in the molecular layer

abnormal cerebellar molecular layer ( J:135408 )

• hypercellular

behavior/neurological

ataxia ( J:135408 )

• subtle ataxic gait, not seen in all homozygotes

growth/size/body

decreased body size ( J:135408 )

cellular

decreased neuronal migration ( J:135408 )

• in migrating granule cells the average distance between the centrosome and nucleus is decreased