All Phenotypes Pde10a<tm1(tTA)Yoko> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pde10a^tm1(tTA)Yoko
targeted mutation 1, Mineto Yokoi
MGI:3794648

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pde10a^tm1(tTA)Yoko/Pde10a^tm1(tTA)Yoko	involves: 129S/SvEv	MGI:3803641

Allelic Composition	Pde10a^tm1(tTA)Yoko/Pde10a^tm1(tTA)Yoko
Genetic Background	involves: 129S/SvEv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde10a^tm1(tTA)Yoko mutation (0 available); any Pde10a mutation (61 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal social investigation ( J:135447 )

• mice have a significant preference for social contact

• total duration of contact is 101.3 seconds compared to 60.1 seconds for wild-type mice

• mean duration of contact is 2.0 seconds compared to 1.4 seconds for wild-type mice

• nose-to-head or nose-to-body investigations happen twice as frequently as in wild-type mice

• there are no differences in olfactory capability, locomotor activity, generalized anxiety, or stress/fear responses

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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