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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppp4ctm1.2Htn
targeted mutation 1.2, Shinji Hirotsune
MGI:3794751
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppp4ctm1.2Htn/Ppp4ctm1.2Htn involves: 129S6/SvEvTac * FVB/N MGI:3794755


Genotype
MGI:3794755
hm1
Allelic
Composition		 Ppp4ctm1.2Htn/Ppp4ctm1.2Htn
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp4ctm1.2Htn mutation (0 available); any Ppp4c mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:134682 )
• homozygous mice died between E4.5 and E7.5, soon after implantation

embryo
inner cell mass degeneration ( J:134682 )
• inner cell mass cells of homozygous null blastocyst explants in culture grew poorly after 3 days and degenerated soon thereafter




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory