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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nrastm1Mok
targeted mutation 1, Moyota Katsuki
MGI:3794957
Summary 15 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nrastm1Mok/Nrastm1Mok either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361199
hm2
 		Nrastm1Mok/Nrastm1Mok involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821334
cx3
 		Krastm1Mok/Kras+
Nrastm1Mok/Nras+ 		B6.129S-Nrastm1Mok Krastm1Mok MGI:4821324
cx4
 		Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok 		either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361200
cx5
 		Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok 		either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361201
cx6
 		Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0 		either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361207
cx7
 		Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Tg(HRAS)2Jic/0 		involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821330
cx8
 		Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0 		involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821332
cx9
 		Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0 		involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821336
cx10
 		Krastm1Mok/Kras+
Nrastm1Mok/Nras+ 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821323
cx11
 		Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nras+ 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821328
cx12
 		Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+ 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821329
cx13
 		Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821331
cx14
 		Hrastm1Mok/Hras+
Nrastm1Mok/Nrastm1Mok 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821333
cx15
 		Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok 		involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821335


Genotype
MGI:4361199
hm1
Allelic
Composition		 Nrastm1Mok/Nrastm1Mok
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:135610 )
• born in normal numbers
• are fertile
• no behavioral defects
• no spontaneous tumors




Genotype
MGI:4821334
hm2
Allelic
Composition		 Nrastm1Mok/Nrastm1Mok
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 2 of 237 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821324
cx3
Allelic
Composition		 Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background		 B6.129S-Nrastm1Mok Krastm1Mok
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 19 of 26 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4361200
cx4
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:135610 )
• born in reduced numbers




Genotype
MGI:4361201
cx5
Allelic
Composition		 Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:135610 )
• do not survive to weaning
perinatal lethality, incomplete penetrance ( J:135610 )
• most deaths occur between E18.5 and birth




Genotype
MGI:4361207
cx6
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0
Genetic
Background		 either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
Tg(HRAS)7Mok mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:135610 )
• born in expected numbers




Genotype
MGI:4821330
cx7
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Tg(HRAS)2Jic/0
Genetic
Background		 involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
Tg(HRAS)2Jic mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:159024 )
N
• no mice exhibit chylous ascites




Genotype
MGI:4821332
cx8
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
Genetic
Background		 involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
Tg(HRAS)2Jic mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:159024 )
N
• no mice exhibit chylous ascites




Genotype
MGI:4821336
cx9
Allelic
Composition		 Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
Genetic
Background		 involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
Tg(HRAS)2Jic mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:159024 )
N
• no mice exhibit chylous ascites




Genotype
MGI:4821323
cx10
Allelic
Composition		 Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 5 of 76 mice develop chylous ascites unlike wild-type mice

immune system
abnormal lymphatic vessel morphology ( J:159024 )
• in the small intestine




Genotype
MGI:4821328
cx11
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nras+
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 2 of 175 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821329
cx12
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 35 of 37 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821331
cx13
Allelic
Composition		 Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 64 of 137 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821333
cx14
Allelic
Composition		 Hrastm1Mok/Hras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (30 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 5 of 153 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821335
cx15
Allelic
Composition		 Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (84 available)
Nrastm1Mok mutation (7 available); any Nras mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
chylous ascites ( J:159024 )
• 6 of 6 mice develop chylous ascites unlike wild-type mice




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory