Analysis Tools
growth/size/body
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• starting at 9 weeks of age, male mice weigh more than littermate controls
• by 20 weeks of age, male mice have gained 15% more weight than controls
• however, female growth curves remain normal
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• liver weight is increased in male mice on an absolute scale but not relative to total body weight
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adipose tissue
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• male mice have significant increases in brown adipose tissue as measured on an absolute scale and normalized to body weight
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• weight of fat in grams for male mice is increased compared to control male mice starting at 6 weeks of age
• by 16 weeks of age, the weight of adipose tissue in male mice is almost double that of male control mice
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• adipocytes in male mice have increased cell size
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• male mice have significant increases in gonadal fat pad weight as measured on an absolute scale and normalized to body weight
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• male mice have significant increases in inguinal fat pad weight as measured on an absolute scale and normalized to body weight
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• male mice have significant increases in retroperitoneal fat pad weight as measured on an absolute scale and normalized to body weight
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• male mice have increased percent body fat starting at 6 weeks of age
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homeostasis/metabolism
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• serum adiponectin levels are about 20% lower in fasted male mice compared to male controls
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liver/biliary system
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• liver weight is increased in male mice on an absolute scale but not relative to total body weight
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