About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pik3catm3Bvan
targeted mutation 3, Bart Vanhaesebroeck
MGI:3795787
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Pik3catm3Bvan/Pik3catm3Bvan
Tg(Tek-cre)1Ywa/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:3796332


Genotype
MGI:3796332
cn1
Allelic
Composition		 Pik3catm3Bvan/Pik3catm3Bvan
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3catm3Bvan mutation (1 available); any Pik3ca mutation (66 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
abnormal vitelline vascular remodeling ( J:136236 )
• by E10.5, mice exhibit a defective remodeling of the primary yolk sac plexus

cardiovascular system
abnormal vascular development ( J:136236 )
• at E10.5, mice develop vascular abnormalities similar to those observed in Pik3catm1Bvan homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory