hematopoietic system
• in response to low concentrations of thrombin and U46619, platelet aggregation is slight decreased compared with similarly treated wild-type cells
• in response to collagen and adenosine diphosphate, platelet aggregation is decreased compared with similarly treated wild-type cells
• in response to GPVI triggering by convulxin, platelet aggregation is abolished unlike similarly treated wild-type cells
• following FeCl3-induced injury, 90% of mice exhibit partial occlusion or fail to form thrombi unlike similarly treated wild-type mice
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homeostasis/metabolism
• in response to low concentrations of thrombin and U46619, platelet aggregation is slight decreased compared with similarly treated wild-type cells
• in response to collagen and adenosine diphosphate, platelet aggregation is decreased compared with similarly treated wild-type cells
• in response to GPVI triggering by convulxin, platelet aggregation is abolished unlike similarly treated wild-type cells
• following FeCl3-induced injury, 90% of mice exhibit partial occlusion or fail to form thrombi unlike similarly treated wild-type mice
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