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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sfrp1tm1Jrbn
targeted mutation 1, Jeffrey Rubin
MGI:3796251
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sfrp1tm1Jrbn/Sfrp1tm1Jrbn involves: 129 * C57BL/6J MGI:3808613


Genotype
MGI:3808613
hm1
Allelic
Composition		 Sfrp1tm1Jrbn/Sfrp1tm1Jrbn
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sfrp1tm1Jrbn mutation (1 available); any Sfrp1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal prostate gland morphology ( J:136160 )
• the prostate appears grossly normal
• there are significantly fewer than normal proliferating cells in the prostate at 5 weeks, the number of proliferating cells is improved by 7 weeks, and proliferating cell numbers more or less normal by 10 weeks
abnormal prostate gland branching morphogenesis ( J:136160 )
• reduced number of distal tips in each prostate lobe

reproductive system
abnormal prostate gland morphology ( J:136160 )
• the prostate appears grossly normal
• there are significantly fewer than normal proliferating cells in the prostate at 5 weeks, the number of proliferating cells is improved by 7 weeks, and proliferating cell numbers more or less normal by 10 weeks
abnormal prostate gland branching morphogenesis ( J:136160 )
• reduced number of distal tips in each prostate lobe




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory