Phenotypes associated with this allele

• Allele Symbol: Fkbp1b^tm1.1Okam
• Allele Name: targeted mutation 1.1, Hiroshi Okamoto
• Allele ID: MGI:3796254
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fkbp1b^tm1.1Okam/Fkbp1b^tm1.1Okam	ICR.129-Fkbp1b^tm1.1Okam	MGI:3807881

Genotype
MGI:3807881

hm1

• Allelic Composition: Fkbp1b^tm1.1Okam/Fkbp1b^tm1.1Okam
• Genetic Background: ICR.129-Fkbp1b^tm1.1Okam

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:136192 )

N • insulin sensitivity normal

N • pancreatic insulin content normal

decreased insulin secretion ( J:136192 )

• impaired insulin secretion in response to glucose

impaired glucose tolerance ( J:136192 )

• higher blood glucose at 15, 30, and 60 minutes after administration

• plasma insulin is lower at 15 and 30 minutes after glucose administration

endocrine/exocrine glands

decreased insulin secretion ( J:136192 )

• impaired insulin secretion in response to glucose