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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdx4tm1.1Gqda
targeted mutation 1.1, George Q Daley
MGI:3796742
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdx4tm1.1Gqda/Cdx4tm1.1Gqda involves: 129S4/SvJae * C57BL/6 MGI:3807073
ot2
 		Cdx4tm1.1Gqda/Y involves: 129S4/SvJae * C57BL/6 MGI:3807072


Genotype
MGI:3807073
hm1
Allelic
Composition		 Cdx4tm1.1Gqda/Cdx4tm1.1Gqda
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx4tm1.1Gqda mutation (0 available); any Cdx4 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryonic erythropoiesis ( J:136405 )
• yolk sac-derived primitive erythroid colony formation is reduced

hematopoietic system
abnormal embryonic erythropoiesis ( J:136405 )
• yolk sac-derived primitive erythroid colony formation is reduced




Genotype
MGI:3807072
ot2
Allelic
Composition		 Cdx4tm1.1Gqda/Y
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx4tm1.1Gqda mutation (0 available); any Cdx4 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryonic erythropoiesis ( J:136405 )
• yolk sac-derived primitive erythroid colony formation is reduced
• hematopoietic expansion is also reduced in blood progenitors derived embryoid bodies or embryonic stem cells

hematopoietic system
abnormal embryonic erythropoiesis ( J:136405 )
• yolk sac-derived primitive erythroid colony formation is reduced
• hematopoietic expansion is also reduced in blood progenitors derived embryoid bodies or embryonic stem cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory