All Phenotypes Tg(Pax2-cre)1Dje MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Pax2-cre)1Dje
transgene insertion 1, Douglas J Epstein
MGI:3797084

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Bmp4^tm1Blh/Bmp4^tm4Blh Tg(Pax2-cre)1Dje/0	involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL	MGI:3805991

Allelic Composition	Bmp4^tm1Blh/Bmp4^tm4Blh Tg(Pax2-cre)1Dje/0
Genetic Background	involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4^tm1Blh mutation (2 available); any Bmp4 mutation (23 available)
Bmp4^tm4Blh mutation (0 available); any Bmp4 mutation (23 available)
Tg(Pax2-cre)1Dje mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

abnormal inner ear morphology ( J:136636 )

• tow thirds of embryos have inner ear defects; more mildly affected embryos show defects in the three ampullae and canals

abnormal semicircular canal morphology ( J:136636 )

• canal defects (in addition to lateral canal truncations) are observed in mildly affected embryos

abnormal utricle morphology ( J:136636 )

• malformed in more severely affected embryos

abnormal vestibular saccule morphology ( J:136636 )

• malformed in more severely affected embryos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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