behavior/neurological
• mice with this mutation lose their balance when rearing
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• mice heterozygous for this mutation exhibit hyperactivity in their home cages
• mutant mice exhibit hyperactivity in an open field (3.3 to 7.6 SD above the mean)
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• some heterozygotes have convulsive seizures after being handled
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nervous system
• some heterozygotes have convulsive seizures after being handled
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