nervous system
N |
• despite abnormal barrel cortex morphology, lesion-induced plasticity of the thalamocortical axonal pattern and synaptic release efficacy are normal
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• while gross barrel patterning is normal, barrel wall formation is disrupted
• dendritic orientation of layer IV neurons in the barrel cortex is impaired and dendritic span is increased compared to in wild-type micedendritic orientation of layer IV neurons in the barrel cortex is impaired and dendritic span is increased compared to in wild-type mice
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• during thalamocorical synapse development
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• AMPA receptor mini-excitatory postsynaptic currents of thalamocortical synapses are smaller than in wild-type mice
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