Analysis Tools
mortality/aging
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• very few mice survive to 3 months of age
|
|
• although mice are born in expected Mendelian ratios, 50% of pups die within 48 hours of birth
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growth/size/body
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• mice are growth retarded
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reproductive system
| N |
• both sexes are fertile, despite a reduction in adult testis size observed in males and in litter size observed in females
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small testis
(
J:250114
)
 |
• testes are smaller at 3 months of age
|
|
|
• testicular weight is reduced at 3 months of age
• however, the ratio of testis weight to body weight is comparable to that of wild-type males and spermatogenesis appears normal
|
 |
• females produce smaller litter sizes, possibly due to their smaller body size
• however, males produce normal litter sizes
|
endocrine/exocrine glands
small testis
(
J:250114
)
|
|
• testes are smaller at 3 months of age
|
|
|
• testicular weight is reduced at 3 months of age
• however, the ratio of testis weight to body weight is comparable to that of wild-type males and spermatogenesis appears normal
|
