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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rgsc197
RIKEN Genomic Sciences Center, 197
MGI:3798983
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Rgsc197/Rgsc197+ involves: C57BL/6JJcl * DBA/2JJcl MGI:3798985


Genotype
MGI:3798985
ht1
Allelic
Composition		 Rgsc197/Rgsc197+
Genetic
Background		 involves: C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgsc197 mutation (1 available); any Rgsc197 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:133634 )
• total serum cholesterol levels of mice with this mutation are diminished (60.7 mg/dL vs. a control range of 86-154 mg/dL)
decreased circulating HDL cholesterol level ( J:133634 )
• high density lipoprotein (HDL) cholesterol levels of mutant mice are diminished (38.9 mg/dL vs. a control range of 55-100 mg/dL)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory