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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Clca1tm1Htzm
targeted mutation 1, Michael Holtzman
MGI:3799070
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Clca1tm1Htzm/Clca1tm1Htzm C57BL/6-Clca1tm1Htzm MGI:3802573


Genotype
MGI:3802573
hm1
Allelic
Composition		 Clca1tm1Htzm/Clca1tm1Htzm
Genetic
Background		 C57BL/6-Clca1tm1Htzm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clca1tm1Htzm mutation (0 available); any Clca1 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
respiratory system phenotype ( J:137274 )
N
• mucus cell metaplasia in response to Sendai virus infection is similar to control mice
• level of airway hyperreactivity in response to inhaled methacholine is similar to controls
• goblet cell metaplasia and airway hyperreactivity in response to OVA injection is similar to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory