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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rgsc273
RIKEN Genomic Sciences Center, 273
MGI:3799205
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Rgsc273/Rgsc273+ involves: C57BL/6JJcl * DBA/2JJcl MGI:3799207


Genotype
MGI:3799207
ht1
Allelic
Composition		 Rgsc273/Rgsc273+
Genetic
Background		 involves: C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgsc273 mutation (1 available); any Rgsc273 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:133634 )
• heterozygous mutants have low total serum cholesterol (66.9 mg/dL vs. a control range of 86-154 mg/dL)
decreased circulating HDL cholesterol level ( J:133634 )
• mice heterozygous for this mutation have low serum high-density lipoprotein (HDL) cholesterol (40.6 mg/dL vs. a control range of 55-100 mg/dL)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory