Phenotypes associated with this allele

• Allele Symbol: Stc2^tm1Rred
• Allele Name: targeted mutation 1, Roger R Reddel
• Allele ID: MGI:3799310
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stc2^tm1Rred/Stc2^tm1Rred	involves: 129S1/Sv * 129X1/SvJ	MGI:4361451
cx2	Stc1^tm1Rred/Stc1^tm1Rred Stc2^tm1Rred/Stc2^tm1Rred	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:4361452

Genotype
MGI:4361451

hm1

• Allelic Composition: Stc2^tm1Rred/Stc2^tm1Rred
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:136007 )

• about 15% heavier than controls

• increased weight only apparent after weaning

• due to increased weight of major organs

• except testes which decrease in weight

increased body length ( J:136007 )

• slightly increased body length

homeostasis/metabolism

abnormal circulating alkaline phosphatase level ( J:136007 )

• levels are 144% of control mouse levels

reproductive system

reproductive system phenotype ( J:136007 )

N • normal reproductive success normal reproductive success

small testis ( J:136007 )

♂ • only major organ to be reduced in size

endocrine/exocrine glands

small testis ( J:136007 )

♂ • only major organ to be reduced in size

Genotype
MGI:4361452

cx2

• Allelic Composition: Stc1^tm1Rred/Stc1^tm1Rred; Stc2^tm1Rred/Stc2^tm1Rred
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

growth/size/body

increased body weight ( J:136007 )

• heavier than controls

• increased weight only apparent after weaning

• due to increased weight of major organs

• except testes which decrease in weight

reproductive system

reproductive system phenotype ( J:136007 )

N • normal reproductive success normal reproductive success

small testis ( J:136007 )

♂ • only major organ to be reduced in size

endocrine/exocrine glands

small testis ( J:136007 )

♂ • only major organ to be reduced in size