All Phenotypes Sox5<tm2.1Vlf> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sox5^tm2.1Vlf
targeted mutation 2.1, Veronique Lefebvre
MGI:3799355

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sox5^tm2.1Vlf/Sox5^tm2.1Vlf	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL	MGI:3800350

Allelic Composition	Sox5^tm2.1Vlf/Sox5^tm2.1Vlf
Genetic Background	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox5^tm2.1Vlf mutation (0 available); any Sox5 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• die at birth

skeleton

abnormal thoracic cage shape ( J:137217 )

• narrow thoracic cage

• delayed mineralization of cervical vertebral bodies

abnormal sternum ossification ( J:137217 )

• irregularly mineralized

craniofacial

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )

digestive/alimentary system

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )

growth/size/body

• failure of the palatal shelves and pterigoid processes to move toward the midline

cleft secondary palate ( J:137217 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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