Analysis Tools
homeostasis/metabolism
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• following ApoB lipoprotein depletion, serum from male mice fed a high fat diet exhibit reduced ABCA1-mediated cholesterol efflux compared with control serum
• however, ABCG1-mediated cholesterol efflux is normal
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• modestly in fasting male mice
• in mice fed a standard chow with 0.01% ezetimibe
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• female mice exhibit an increase in cholesteryl ester content in the liver compared with wild-type mice
• however, liver free cholesterol content is normal
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• in female mice fed standard chow
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liver/biliary system
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• in female mice fed standard chow
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cellular
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• following ApoB lipoprotein depletion, serum from male mice fed a high fat diet exhibit reduced ABCA1-mediated cholesterol efflux compared with control serum
• however, ABCG1-mediated cholesterol efflux is normal
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