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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Map3k9tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3800581
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Map3k9tm1Lex/Map3k9tm1Lex 129S-Map3k9tm1Lex MGI:3801186
cx2
Map3k10tm1Lex/Map3k10tm1Lex
Map3k9tm1Lex/Map3k9tm1Lex
either: 129S-Map3k10tm1Lex Map3k9tm1Lex or B6.129S-Map3k10tm1Lex Map3k9tm1Lex MGI:3801188


Genotype
MGI:3801186
hm1
Allelic
Composition
Map3k9tm1Lex/Map3k9tm1Lex
Genetic
Background
129S-Map3k9tm1Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k9tm1Lex mutation (0 available); any Map3k9 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice exhibit no morphological defects




Genotype
MGI:3801188
cx2
Allelic
Composition
Map3k10tm1Lex/Map3k10tm1Lex
Map3k9tm1Lex/Map3k9tm1Lex
Genetic
Background
either: 129S-Map3k10tm1Lex Map3k9tm1Lex or B6.129S-Map3k10tm1Lex Map3k9tm1Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k10tm1Lex mutation (0 available); any Map3k10 mutation (34 available)
Map3k9tm1Lex mutation (0 available); any Map3k9 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• despite a lack of compensation from Map3k11, mice have normal life spans

reproductive system
N
• despite a lack of compensation from Map3k11, mice breed normally
• despite expression in the testis, testicular development is normal

embryo
N
• despite a lack of compensation from Map3k11, mice develop normally

muscle
N
• despite expression in the femoral muscle, skeletal muscle organization is normal

nervous system
N
• despite expression in the brain, nervous system development and cell death in the superior cervical ganglia are normal

renal/urinary system
N
• despite endogenous expression in the kidneys, renal morphology and function are normal

digestive/alimentary system
N
• despite expression in the spleen and stomach, their morphology and function are normal





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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory