About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Map3k9tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3800581
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Map3k9tm1Lex/Map3k9tm1Lex 129S-Map3k9tm1Lex MGI:3801186
cx2
Map3k10tm1Lex/Map3k10tm1Lex
Map3k9tm1Lex/Map3k9tm1Lex
either: 129S-Map3k10tm1Lex Map3k9tm1Lex or B6.129S-Map3k10tm1Lex Map3k9tm1Lex MGI:3801188


Genotype
MGI:3801186
hm1
Allelic
Composition
Map3k9tm1Lex/Map3k9tm1Lex
Genetic
Background
129S-Map3k9tm1Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k9tm1Lex mutation (0 available); any Map3k9 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice exhibit no morphological defects




Genotype
MGI:3801188
cx2
Allelic
Composition
Map3k10tm1Lex/Map3k10tm1Lex
Map3k9tm1Lex/Map3k9tm1Lex
Genetic
Background
either: 129S-Map3k10tm1Lex Map3k9tm1Lex or B6.129S-Map3k10tm1Lex Map3k9tm1Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k10tm1Lex mutation (0 available); any Map3k10 mutation (34 available)
Map3k9tm1Lex mutation (0 available); any Map3k9 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• despite a lack of compensation from Map3k11, mice have normal life spans

reproductive system
N
• despite a lack of compensation from Map3k11, mice breed normally
• despite expression in the testis, testicular development is normal

embryo
N
• despite a lack of compensation from Map3k11, mice develop normally

muscle
N
• despite expression in the femoral muscle, skeletal muscle organization is normal

nervous system
N
• despite expression in the brain, nervous system development and cell death in the superior cervical ganglia are normal

renal/urinary system
N
• despite endogenous expression in the kidneys, renal morphology and function are normal

digestive/alimentary system
N
• despite expression in the spleen and stomach, their morphology and function are normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory