Analysis Tools|
Allele Symbol Allele Name Allele ID |
Cd207tm1(Hbegf/EGFP)Bjec targeted mutation 1, Bjorn E Clausen MGI:3800754 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• contact hypersensitivity assessed by ear swelling is attenuated at 24 hours after hapten challenge (mice were treated with diptheria toxin to induce deletion of Cd207 postive dendritic cells)
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• following intratracheally treatment with diphtheria toxin, CD11b-CD11chi dendritic ccells are depleted in the lungs
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• following treatment with diphtheria toxin, mice exhibit a rapid and complete ablation of Langerhans cells and recovery does not occur for 4 weeks
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• following treatment with diphtheria toxin
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• following intratracheally administration of diphtheria toxin, mice exhibit increased severity of influenza infection, increased weight lose and delayed clearance compared to infected wild-type mice
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• following intratracheally treatment with diphtheria toxin, CD11b-CD11chi dendritic ccells are depleted in the lungs
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• following treatment with diphtheria toxin, mice exhibit a rapid and complete ablation of Langerhans cells and recovery does not occur for 4 weeks
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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