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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Oxtrtm1.1Wsy
targeted mutation 1.1, W Scott Young III
MGI:3800791
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Oxtrtm1.1Wsy/Oxtrtm1.1Wsy involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:3801097
cn2
 		Oxtrtm1.1Wsy/Oxtrtm1.1Wsy
Tg(Camk2a-cre)1Szi/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL MGI:3801098


Genotype
MGI:3801097
hm1
Allelic
Composition		 Oxtrtm1.1Wsy/Oxtrtm1.1Wsy
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oxtrtm1.1Wsy mutation (1 available); any Oxtr mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3801098
cn2
Allelic
Composition		 Oxtrtm1.1Wsy/Oxtrtm1.1Wsy
Tg(Camk2a-cre)1Szi/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oxtrtm1.1Wsy mutation (1 available); any Oxtr mutation (41 available)
Tg(Camk2a-cre)1Szi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:137445 )
• weigh less than control mice
• weight discrepancy relative to controls increases with age

endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:137445 )
N
• normal milk production

behavior/neurological
abnormal social investigation ( J:137445 )
• less time spend by males investigating either familiar or novel females during second trials
• 5-trial recognition studies indicated no difference between mutant mice and controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory