Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(TcrLCMV)318Sdz transgene insertion 318, Birgit Ledermann MGI:3801008 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• adoptive transfer experiments demonstrate that reduced expansion of virus-specific CD8+ T cells is cell intrinsic and host independent
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• only weak signs of hepatitis (less than 100 U/L) after LCMV infection
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• only weak signs of hepatitis (less than 100 U/L) after LCMV infection
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• a reduction of CD8 single-positive (SP) thymocytes expressing the tg TCR
• the periphery exhibits an 8- to 10-fold decrease compared with that of single-tg TCR mice
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• a reduction of CD8 single-positive (SP) thymocytes expressing the tg TCR
• the periphery exhibits an 8- to 10-fold decrease compared with that of single-tg TCR mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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